We’re excited to kick off a brand-new season of the SFRR-E ECR webinar series “Emerging Leaders in Redox Biology”! 

This series is all about giving early-career researchers a stage to share their fresh perspectives and innovative work in the redox field. We’re thrilled to welcome you back after the summer break, and we can’t wait to learn, connect, and spark new discussions together. The first webinar of the series will take place on September 2nd, 2025, at 15:00 CET, diving into the fascinating topic of “Redox regulation in cellular aggregates” with two outstanding speakers, Avilien Dard and Thibaut Vignane.

Unveiling redox-regulation of protein phase separation during heat stress

Avilien Dard, PhD

Center for Plant Systems Biology, Vlaams Instituut voor Biotechnologie, Ghent University, Belgium

My journey in plant sciences integrates plant adaptation to environmental stress, redox mechanisms, and epigenetics. Trained at the University of Perpignan Via Domitia and the University of Toulouse Paul Sabatier in France, I developed expertise in molecular biology and genetics, laying the foundation for my research career. In October 2019, I commenced my PhD under Dr. Jean-Philippe Reichheld's supervision at the Laboratory of Plant's Genome and Development in Perpignan, France. Our research revealed redox mechanisms' significance in plant adaptation to heat waves and their impact on chromatin regulators, including histone deacetylases HDA6 and HDA19. After defending my thesis successfully in May 2023, I began my first postdoc in Prof. Dr. Frank Van Breusegem's lab at VIB-Ugent Center for Plant System Biology in Ghent, Belgium. My initial project focused on uncovering redox-sensitive proteins in the nucleus using redox proteomics. In April 2024, I secured the prestigious MSCA postdoc fellowship to initiate my independent research within the same team. This project involves developing new tools like genetically encoded redox proteomics probes and biosensors to investigate the role of redox regulation in stress granule formation during heat stress.

 

Protein thiol alterations drive pathologic liquid-liquid phase separation in the aging brain

Thibaut Vignane, PhD

Institute of Molecular Systems Medicine, Goethe University Frankfurt am Main, Germany

My scientific focus lies at the intersection of redox regulation, cellular stress, and aging, with a particular interest in how redox control shapes protein condensates. After completing my Master’s degree in Molecular Genetics at the University of Bordeaux, I moved to Germany in 2020 to pursue a PhD in Prof. Milos Filipović’s group (ERC – Sulfaging) at the University of Cologne and ISAS Dortmund. My doctoral research revealed how age-induced imbalances in cysteine-based post-translational modifications, especially sulfenylation and persulfidation, disrupt protein phase separation and can promote pathological aggregation. Following the defense of my thesis in December 2024, I joined Prof. Christina Münch’s lab at the Institute of Molecular Systems Medicine in Frankfurt am Main for my first postdoctoral position, where I continue to study redox signalling in the context of mitochondrial stress.

Don’t miss this great start to the series! Mark your calendars, spread the word, and join us online for an inspiring session! We look forward to seeing you there and to another season of exciting science and lively discussions with the SFRR-E ECR community.

Want to know more about what we do? You’ll find all the info about the ECR Subcommittee on the SFRR-E website.

For regular updates, follow us on Instagram (@sfrr_ecr), Bluesky (@sfrre-ecr.bsky.social‬) Twitter/X (@SFRR_Europe), and LinkedIn (SFRR-E).

Got a question, idea, or just want to say hi? Drop us an email at This email address is being protected from spambots. You need JavaScript enabled to view it. - we’d love to hear from you!

How can I join the webinar?

https://us06web.zoom.us/j/86469731540?pwd=cQW0yK5sNCPXO5sSOcaoBHaZPy2Tu8.1 
Passcode: 433382

The ECR Subcommittee Team
SFRRE ECR webpage

Dear colleagues, 

In today's newsletter we would like to announce the opening of the mentoring programme for 2025 and highlight funding opportunities for ECR members of our society! We would like to celebrate the conclusion of our webinar series and discuss with you future directions for next year. At the end of the newsletter, as always, you can also find a collection of upcoming events with important deadlines, some suggestions of interesting redox reads recently published, open call for papers and job opportunities for young redox researchers. And if you are interested in our activities planned for the SFRR-International Galway meeting, stay tuned! More details are coming soon! We cannot wait to see you all there!

Mentoring Programme 2025:

We are very pleased to announce the launch of the next round of the mentoring programme! Joining a mentoring programme, whether as a mentor or a mentee, offers substantial benefits for both personal and professional development:

As a Mentor:

1. Give Back: Share your experience to help someone grow, and contribute to your community or profession.
2. Improve Leadership & Communication Skills: Teaching others refines your ability to explain, coach, and lead effectively.
3. Gain Fresh Perspectives: Mentees often bring new ideas, questions, or insights that challenge your own thinking.
4. Build Your Reputation: Being seen as a mentor enhances your credibility and visibility in your field.
5. Learn Through Teaching: Articulating your own experience can deepen your understanding and highlight gaps you didn’t notice before.

As a Mentee:

1. Accelerate Learning: Get guidance that helps you avoid common mistakes and learn faster.
2. Gain Confidence: Support from a mentor can boost your belief in your abilities and direction.
3. Access Experience & Insight: Learn from someone who’s already walked the path you're on.
4. Expand Your Network: Mentors can open doors to people, opportunities, or resources you wouldn’t otherwise reach.
5. Career Development: Mentorship can help you set clear goals, stay accountable, and build a roadmap for your ambitions.

We are strongly encouraging participation from all our community members! Only with your support can this programme work! The programme is open for registrations for both mentors and mentees. If you log in into the society’s intranet https://intranet.sfrr-europe.org, you can find the link to the quick survey on the left hand site “Mentoring Programme 2025“, it will only take 10 minutes! Deadline to sign up: 10th June 2025. For any questions please contact This email address is being protected from spambots. You need JavaScript enabled to view it..

Webinar series “Emerging leaders in redox biology”

Our webinar series completed its third year! We had some fantastic speakers this year and we are really looking forward to the next round of super cool talks from all you early career members and future leaders of our society! The webinar series will continue again in Autumn 2025!

Inspired by your feedback, we are pleased to announce a new, parallel seminar series to the “Emerging leaders in redox biology” webinars, focused on developing the skills needed to excel in research. Send us the topics you want to learn more about from the experts! Is it grant writing? Narrative CV composition? Effective presentation and communication? Email us your thoughts at This email address is being protected from spambots. You need JavaScript enabled to view it., or write to our instagram account!

A recap of the last “Emerging Leaders in Redox Biology” webinars

In May, we had the webinar that is always very special for us. May is the Mental Health Awareness month and we wanted to share some insights about mental health with all of you. Our webinar featured speaker Amal Ibrahim, who gave an amazing presentation on stress factors for students.

Stress Factors, Stress Levels, and Coping Mechanisms Among University Students

Amal Ibrahim

Faculty of Health Sciences, University of Jaén, Spain

Amal Ibrahim is a certified healthcare quality professional by the National Association for Healthcare Quality (NAHQ), USA. She earned her master’s degree in health management and policies from Al-Quds University, Palestine, in 2018. Currently, she is a PhD student in the Health Sciences program at the University of Jaén, specializing in health management research, and a part-time lecturer at the Arab American University of Palestine.
Previously, Amal worked as a project coordinator for NGOs in Palestine, where she coordinated a project with the University of Jaén. She also served as a Middle East coordinator for a British event organization company in the UK, earning the Best Coordinator Award in 2020. Additionally, she has experience as a medical referral coordinator at a private hospital in Palestine and worked with the World Bank, providing administrative and management support to external experts. Earlier in her career, she worked as an administrative assistant in Saudi Arabia, where she was honored as Employee of the Year in 2012.
Her research has been published in The Scientific World Journal (2023, 2026971) and Eastern Mediterranean Health Journal (EMHJ, Vol. 28, No. 10, 2022). She is passionate about contributing her expertise in healthcare management and policy development.
In the May webinar, Amal highlighted the growing awareness of mental health challenges within academia. She addressed how intense workloads, pressure to publish, job insecurity and academic isolation contribute to rising levels of anxiety, depression and burnout, particularly among PhD students and early-career researchers. While individual strategies such as boundary-setting, peer support and self-care are valuable, she emphasized that lasting change requires systemic efforts to build a more sustainable, supportive and inclusive environment. The session concluded with a call to action for individuals, institutions and policy-makers to collaborate in fostering a healthier academic culture.

 

In April’s webinar we learnt about “Chaperones in redox biology” with two wonderful talks by Kathrin Ulrich and Reymond Sutandy. If you didn’t have a chance to follow the webinar, here’s a summary for you.

Redox-regulated chaperones in organismal proteostasis regulation

Kathrin Ulrich, PhD

Institute of Biochemistry, Center of Molecular Biosciences, CoMB, University of Cologne

Keep calm and chaperone on - In this webinar, Dr. Kathrin Ulrich shared with us how the redox state of Get3 can modulate its function. Get3 is a cytosolic protein that, when reduced, has an ATPase function that ultimately facilitates the post-translational insertion of tail-anchored proteins into the membrane of the endoplasmic reticulum. Yet, upon oxidative stress and a depletion of ATP, Get3 loses its nucleotide-binding capacities, making the cysteines available for oxidation, partially unfolding Get3 and re-arranging the protein, changing its function as a chaperone, where it can form chaperone-active oligomers, helping the cell to cope against unfavourable conditions. Get3 functions then, as a stress-sensing protein, able to moonlight between its functions as an ATPase and a Chaperone, depending on the requirements of the cell. The webinar was not recorded, but you can find more of Dr. Ulrich's research on her group’s website: https://ulrichlab.uni-koeln.de

ROS-mediated signaling of the mitochondrial unfolded protein response

Reymond Sutandy, PhD

University of Kansas Medical Center, Kansas, USA

When the Powerhouse sends an SOS - In this webinar, Dr. Raymond Sutandy guided us to understand the signaling mechanisms that activate the mitochondrial unfolded protein response (UPRmt) in human cells. He showed that UPRmt is triggered by two independent signals from the mitochondria, mitochondrial reactive oxygen species (mtROS), and the accumulation of mitochondrial protein precursors in the cytosol. mtROS diffuse to the cytosol, and it is detected by the DNAJA1-HSP70 complex, activating the nuclear translocation of the transcription factor, HSF1, and changing the transcriptomic landscape of the cell, inducing the mitochondrial chaperones and proteases to restore proteostasis in the mitochondria. Inhibiting either the production of mtROS or the accumulation of the protein precursors prevents the activation of HSF1 and therefore the UPRmt response. Showing that the disruption of this pathway will make mitochondria more vulnerable, reducing cell survival in unfavourable conditions.

Remember that you can also watch recordings of the webinars through the SFRR-E intranet!

More information about the ECR Subcommittee can be found on the SFRR-E website (ECR Committee), while regular updates can be found on Twitter (@SFRR_Europe), Instagram (@sfrr_ecr) and LinkedIn (SFRR-E). For any question or suggestion you might have, you can contact us via email: This email address is being protected from spambots. You need JavaScript enabled to view it..

Hope to see you online for our next Webinar Series appointment,

The ECR subcommittee

Upcoming events:

22nd SFRRI Biennial Meeting

• The New Era of Redox Biology: from Basic Biochemistry to Redox Omics
• 3 - 6 June 2025
• Location: Galway, Ireland
• Deadlines:
  • Early Bird Registration and abstract submission for poster presentation: 4 April 2025
  • Further information: https://www.sfrrgalway2025.com

 

12th Meeting of the Canadian Oxidative Stress Consortium (COSC)

• 11 - 13 June 2025
• Location: York University, Toronto, Canada
• Further information: https://rame.fluid.events/2025COSC?pgid=55846

 

FASEB Science Research Conference. Ferroptosis, Oxidative Stress, and Lipid Metabolism

• 27 - 31 July 2025
• Location: Scottsdale, Arizona
• Deadlines:
  • Abstract Submission: 1 June 2025
  • Early Registration: 15 June 2025
  • Housing: 13 July 2025
• Further information: https://events.faseb.org/event/11797f9e-df16-42b9-9c47-f1e06713c4fb/summary

 

 

9th International Workshop on Nitric Oxide and Cancer

• Special focus on Inflammation and Therapeutics
• 8 - 10 September 2025
• Location: Dijon, France
• Deadlines:
  • Registration: July 20, 2025
  • Further information: https://blog.u-bourgogne.fr/no-cancer-dijon2025/

 

EMBO Workshop: Thiol based redox switches: From chemistry to physiology and pathology

• 13 - 18 September 2025
• Location: Sant Feliu de Guixols, Spain
• Abstract Submission Deadline: 31 May 2025
• Further information: https://meetings.embo.org/event/25-thiol-switches

 

 

FEBS 2nd Redox Medicine Workshop

• Connecting the Exposome with Redox Regulation in Health and Disease
• 6 - 9 October 2025
• Location: Luso, Portugal
• Abstract Submission Deadline: 20 July 2025
• Travel Grants: FEBS YTF Grants and SFRR-E Bursaries. Deadline: 1 July 2025
• Further information: http://www.redoxmedicine2025.febsevents.org/

 

 

SfRBM 2025 - 32nd Annual Conference of the Society for Redox Biology & Medicine

• 19 - 22 November 2025
• Location: Capital Hilton, Washington DC
• Abstract Submission Deadline: 5 September 5 2025
• Further information: https://sfrbm.org/meetings/sfrbm-2025/

 

 

Interesting Redox Papers:

• Mathieu, J., Kriznik, A., Charron, C., et al. The Dual Role of Active Site Hydroxylated Residue in Peroxiredoxin Sulfinylation Catalysis. Antioxid Redox Signal (2025). https://doi.org/10.1089/ars.2024.0685
• Villar, S.F., Ferrer-Sueta, G. & Denicola, A. Different oligomerization dynamics of reduced and oxidized human peroxiredoxin 1 and 2. Biochem Biophys Res Commun (2025). https://doi.org/10.1016/j.bbrc.2025.151392
• Roeck, B.F., Lotfipour Nasudivar, S., Vorndran, M.R.H. et al. Ferroptosis spreads to neighboring cells via plasma membrane contacts. Nat Commun (2025). https://doi.org/10.1038/s41467-025-58175-w
• de Bont, L., Donnay, N., Favier, F., et al. Novel atypical thioredoxins with potential redox activity in eukaryote photosynthetic organisms. J Exp Bot (2025). https://doi.org/10.1093/jxb/eraf066
• Frattini, G., Puzzolo, J.L., Drusin, S.I., et al. Human Mn-superoxide dismutase acetylation protects from enzyme nitration and inactivation. Arch Biochem Biophys (2025). https://doi.org/10.1016/j.abb.2025.110439
• Kim, D., Kesavan, R., Ryu, K., et al. Mitochondrial NADPH fuels mitochondrial fatty acid synthesis and lipoylation to power oxidative metabolism. Nat Cell Biol (2025). https://doi.org/10.1038/s41556-025-01655-4
• Singh, G., Vengayil, V., Khanna, A., et al. Active control of mitochondrial network morphology by metabolism-driven redox state. Proc Natl Acad Sci U S A (2025). https://doi.org/10.1073/pnas.2421953122
• Yang, J-S., Morris, A.J., Kamizaki, K., et al. ALDH7A1 protects against ferroptosis by generating membrane NADH and regulating FSP1. Cell (2025). https://doi.org/10.1016/j.cell.2025.03.019
• Aleixo-Silva, R.L., Domingos, R.M., Trujillo, M., et al. Interaction between 1-Cys peroxiredoxin and ascorbate in the response to H2O2 exposure in Pseudomonas aeruginosa. Redox Biol (2025). https://doi.org/10.1016/j.redox.2025.103658

Newest Redox Protocols:

• Pérez-Chávez, I., Baeyens, N., Ezeriņa, D., et al. Protocol for real-time glycolytic monitoring in mammalian cells using confocal microscopy and HYlight, a biosensor for fructose 1,6-bisphosphate. STAR Protoc (2025). https://doi.org/10.1016/j.xpro.2025.103792

 

Insightful Redox Reviews:

• Cortese-Krott, M.M., Berra, L., Hobbs, A., et al. New Directions for Nitric Oxide – Focused, Rapid, and Forward-Looking. Nitric Oxide (2025). https://doi.org/10.1016/j.niox.2025.04.005
• Ugalde, J.M. & Meyer, A.J. Genetically encoded biosensors as gateways to retrograde redox signalling in live plants. J Exp Bot (2025). https://doi.org/10.1093/jxb/eraf080
• Niemeier, J-O, Prates Roma, L., Riemer, J., et al. Monitoring subcellular NADP redox state with NAPstar biosensors. Trends Biochem Sci (2025). https://doi.org/10.1016/j.tibs.2025.03.013
• Lee, K.S., Su, X. & Huan, T. Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics. Nat Metab (2025). https://doi.org/10.1038/s42255-025-01283-0
• Latest Redox Preprints:Melicher, P., Dvořák, P., Tsinyk, M., et al. Protein and genetic interactions between RACK1A and FSD1 modulate plant development and stress granule-dependent response to salt in Arabidopsis. BioRxiv (2025) https://doi.org/10.1101/2025.02.25.640159
• Bellalta, S., Pinheiro-Machado, E., Prins, J., et al. Disrupted stemness and redox homeostasis in mesenchymal stem cells of neonates from mothers with obesity: implications for increased adiposity. BioRxiv (2025). https://doi.org/10.1101/2025.04.14.648714
• Zaki, A.G., Miri, S.M., Vatandaşlar, E., et al. Switching ON Hydrogen Sulfide: A Chemogenetic Toolkit for Spatially Resolved H2S Manipulation. BioRxiv (2025). https://doi.org/10.1101/2025.05.12.653628

Call for papers:

• Journal: Redox Biochemistry and Chemistry
• Special Issue: Spatial analysis and new methods of identifying and quantifying intracellular oxidants
• Submission deadline: 31 August 2025
• More information:
• https://www.sciencedirect.com/special-issue/320420/spatial-analysis-and-new-methods-of-identifying-and-quantifying-intracellular-oxidants

 

Redox Job Opportunities:

Remember that if there’s an open position in your lab for early career researchers and you would like to advertise it in our newsletter, just write us an email (This email address is being protected from spambots. You need JavaScript enabled to view it.) containing the following information:

• Kind of position: (PhD student, Postdoc, etc)
• Research topic
• Institute/University
• Deadline
• Contact information
• Further information about the position (if any)

Dear colleagues, 

We have wonderful news! We are delighted to announce that the ECR subcommittee has five new members! We are really excited to see what they bring to the team and look forward to working together on exciting new initiatives!

In today's newsletter, we will acknowledge the hard work from our past members and we will introduce you to our new members. We will also announce the upcoming April’s webinar discussing chaperones in redox biology and share with you a summary of March’s webinar. At the end of the newsletter, as always, you can also find a collection of upcoming events with important deadlines, some suggestions of interesting redox reads recently published, open call for papers and job opportunities for young redox researchers.

Good people go…

Last year, we bid farewell to some of our valued members.

• Carmen Castell: She first took charge of our LinkedIn account before transitioning to the webinar team, where she was responsible for the communications with the webinar invited speakers. She was known as our plant girl and, without a doubt, the best dancer!
• Eduardo Fuentes Lemus: As one of the founding members, he played a key role in conceptualizing and creating both the mentoring program and the editorial mentoring program. His kindness and professionalism left a lasting impression.
• Nikos Margaritelis: Nikos helped bring our webinar series to life and was also involved in the social media team. He was the creative force behind many of our initiatives, always full of original ideas. He was also the soul of our subcommittee—always ready for a good laugh, a good beer (via zoom or in person), and a reminder of the importance of numbers and statistics.
• Valeria Scalcon: A founding member and one of the masterminds behind our webinar series, Valeria was known for being the tallest member of the subcommittee, her incredible sense of humor, her impeccable organisation skills and her natural talent for teaching.

Saying goodbye is never easy, especially to people who have had such a meaningful impact on our lives. These ECR subcommittee members were not just essential contributors—they became our friends and an irreplaceable part of our redox family. We will miss them dearly, but their legacy will always remain a part of what we do.

…and new people come! Meet the new members of the ECR subcommittee!

Our subcommittee has recently welcomed five new members! We are excited to introduce them and look forward to the fresh ideas and energy they will bring. Meet our new members below!

Alina Sigaeva

I am a postdoc at SciLifeLab and KTH Royal Institute of Technology in Stockholm, Sweden, where I am working on bringing together spatial proteomics and redox biology.

I studied cell biology and histology at Lomonosov Moscow State University, and during that time I was working on the effects of visible light spectrum on the ageing of the eyes. Ageing made me interested in oxidative stress, and for my PhD I joined Prof. Romana Schirhagl’s group in Groningen, the Netherlands. During my PhD project, I was developing and validating new nanoparticle-based sensors that now allow us to use quantum effects to detect free radicals in live cells with extremely high sensitivity and resolution. Being a biologist and working with physicists and engineers was challenging, but fun and extremely rewarding, and I could not have imagined a better environment. Over these years, I have also been involved in the organization of the Symposium for Biology Students in Europe, an event for Biology students from all fields and backgrounds, which has made me appreciate the importance of different perspectives and interdisciplinary dialogue even more. After my PhD I received a Rubicon fellowship from Dutch Research Council to spend 2 years in Sweden, at Prof. Emma Lundberg’s lab, where I am currently working with some wonderful people in a quest to bridge the fields of spatial proteomics and redox metabolism.

What annoys you in the lab?
Running out of pipette tips and having to walk to the storage room to fetch those.

What do you like to do the most in the lab?
I could spend hours at the confocal microscope.

What is your favourite thing to do for celebrating a successful experiment?
It usually means having some breathtakingly beautiful images to show, so I share those with my colleagues (and friends). Afterwards, there’s usually a relaxing evening at home.

Which was your first spot in your lab coat?
Probably hematoxylin, eosin, or some other histological stain.

 

Avilien Dard

I am a postdoc at VIB-Ugent Center for Plant System Biology in Ghent, Belgium, where I am working on redox regulation in stress granule formation during heat stress.

My journey in plant sciences integrates plant adaptation to environmental stress, redox mechanisms, and epigenetics. Trained at the University of Perpignan Via Domitia and the University of Toulouse Paul Sabatier in France, I developed expertise in molecular biology and genetics, laying the foundation for my research career. In October 2019, I started my PhD under Dr. Jean-Philippe Reichheld's supervision at the Laboratory of Plant's Genome and Development in Perpignan, France. Our research revealed redox mechanisms' significance in plant adaptation to heat waves and their impact on chromatin regulators, including histone deacetylases HDA6 and HDA19. After defending my thesis successfully in May 2023, I began my first postdoc in Prof. Dr. Frank Van Breusegem's lab at VIB-Ugent Center for Plant System Biology in Ghent, Belgium. My initial project focused on uncovering redox-sensitive proteins in the nucleus using redox proteomics. In April 2024, I secured the prestigious MSCA postdoc fellowship to initiate my independent research within the same team. This project involves developing new tools like genetically encoded redox proteomics probes and biosensors to investigate the role of redox regulation in stress granule formation during heat stress.

What annoys you in the lab?
Finding empty stock boxes!

What do you like to do the most in the lab?
Confocal imaging

What is your favourite thing to do for celebrating a successful experiment?
Enjoying a good beer with the team

Which was your first spot in your lab coat?
Coomassie blue probably

 

Chantalle Moulton

I am a postdoctoral researcher in the Human Longevity Program at IRCCS San Raffaele in Rome, Italy. My current research focuses on the role of redox biology in aging and neuroinflammation by combining molecular and cellular biology with nanotechnology to optimise biomimetic nanoparticles for targeted drug delivery in the brain.

My academic journey began with a bachelor’s degree in Human Physiology, Genetics, and Psychology at the University of Pretoria, South Africa, where I developed a fascination for the molecular mechanisms at play in everyday life and also in pathology. This led me to pursue an interdisciplinary master’s degree in Health and Physical Activity taught by a cohort of European institutions, where I explored the role of extracellular vesicles in redox homeostasis after exercise in trained and untrained individuals. I then continued with a PhD at the University of Rome “Foro Italico,” where I investigated the impact of physical activity on DNA methylation, biological aging, and oxidative stress in breast cancer patients undergoing medical treatment.

Now, as a postdoc researcher, I am exploring how redox mechanisms contribute to neurodegeneration, neuroinflammation, and aging, and how we can treat related conditions via targeted drug delivery to the brain using biomimetic nanoparticles. Over my career, attending SFRR-E meetings has been a great experience, reinforcing my interest for redox research and interdisciplinary collaboration. I look forward to contributing to this scientific community and continuing to investigate the role of oxidative stress in health and disease.

What annoys you in the lab?
Failed experiments and western blots.

What do you like to do the most in the lab?
Brainstorming new experiments.

What is your favourite thing to do for celebrating a successful experiment?
Excitedly declaring “It worked!” to anyone that will listen.

Which was your first spot in your lab coat?
I think silver nitrate stains back in bachelor’s chemistry.

 

Marin Kuntic

I am a postdoctoral researcher in the Department of Molecular Cardiology at the University Medical Center Mainz, Mainz, Germany. My research focuses on the effects of environmental and behavioural risk factors on the cardiovascular system.

My scientific interests started during my high school years, as I was involved in a training program for talented youth in Serbia. I went on to study physical chemistry at the University of Belgrade, Serbia, where I obtained a Bachelor’s degree and a Master’s degree with the focus on biophysical chemistry. After this, I went to Germany where I obtained a PhD in the field of translational biomedicine, with the focus on molecular cardiology. My PhD thesis and my current research focus on the effects of environmental (noise and air pollution) and behavioural (smoking and diet) risk factors on the cardiovascular system in mouse models. I would like to continue my research career and lead my own lab one day.

What annoys you in the lab?
Lack of management.

What do you like to do the most in the lab?
Write papers.

What is your favourite thing to do for celebrating a successful experiment?
Go home early.

Which was your first spot in your lab coat?
Concentrated HCl. It was more of a hole than a spot.

 

Tim Baldensperger

I am a Moritz Schlick Postdoctoral Fellow in protein chemistry at the University of Vienna. My research focuses on the molecular mechanisms of aging and age-related diseases. I study how cellular stressors such as reactive oxygen species, acyl-CoA species, α-dicarbonyls, and formaldehyde influence posttranslational modifications and protein aggregation.

I studied Food Chemistry at Martin Luther University Halle-Wittenberg and joined the research training group “Protein Modifications: A Key Mechanism in Aging” as a PhD student to investigate how posttranslational modifications change during aging. For my first postdoctoral position, I joined Tilman Grune’s lab at the German Institute of Human Nutrition, where I elucidated cytotoxic effects of the oxidatively crosslinked protein aggregate lipofuscin. In 2023 I relocated to Vienna and aim to establish my own junior research group “Posttranslational Modifications in Neurodegenerative Diseases” under the mentorship of Christian Becker.

What annoys you in the lab?
When I am ready to start an experiment, only to find that an essential chemical is empty because someone forgot to reorder it.

What do you like to do the most in the lab?
I enjoy working with analytical instruments like flow cytometry and mass spectrometry. These high-tech instruments are extremely fascinating and it is a huge privilege to operate them.

What is your favorite thing to do for celebrating a successful experiment?
I like to celebrate the successful completion of a project with a nice dinner at a great restaurant.

Which was your first spot in your lab coat?
Countless holes from acid splashes in “Introduction to Inorganic Chemistry”.

 

Next Webinar series “Emerging leaders in redox biology”

The next webinar will take place on April 1st, 2025, at 15:00 CET, focusing on the topic “Chaperones in redox biology” with featured speakers Kathrin Ulrich and Reymond Sutandy.

 

Redox-regulated chaperones in organismal proteostasis regulation

Kathrin Ulrich, PhD
Institute of Biochemistry, Center of Molecular Biosciences, CoMB, University of Cologne

Kathrin received her PhD in 2017 at Heidelberg University where she worked in the lab of Luise Krauth-Siegel on oxidative thiol modifications in African trypanosomes. As a postdoc, she joined the lab of Ursula Jakob at the University of Michigan to study redox-regulated chaperones and their roles in cell stress responses. Since Oct 2022, she is Juniorprofessor for Cellular Biochemistry at the University of Cologne. Her research group focuses on redox regulation of chaperones and their role in maintaining a healthy proteome during aging and environmental stresses. https://ulrichlab.uni-koeln.de 

 

 

ROS-mediated signaling of the mitochondrial unfolded protein response

Reymond Sutandy, PhD
University of Kansas Medical Center, Kansas, USA

Reymond Sutandy is a molecular biologist currently establishing his independent lab as a Principal Investigator at the Institute of Molecular Systems Medicine within the Medical Department of Goethe University Frankfurt. He earned his B.Sc. from Bandung Institute of Technology, Indonesia, in 2011, and his M.Sc. from National Central University, Taiwan, in 2013. For his doctoral studies, Reymond moved to Germany, completing his Ph.D. in 2019 in molecular biology at Johannes Gutenberg University Mainz. His doctoral research, conducted at the Institute of Molecular Biology under Dr. Julian König, focused on alternative splicing regulation by examining transcriptome-wide RNA-protein interactions. Following his Ph.D., Reymond joined the lab of Prof. Christian Münch as a postdoctoral researcher at the Institute of Biochemistry II, Goethe University Frankfurt. There, he investigated the mitochondrial unfolded protein response (UPRmt), a proteostasis pathway triggered by the accumulation of misfolded proteins in mitochondria. His research revealed that UPRmt activation in humans is signaled by two critical mitochondrial-derived molecules: reactive oxygen species (ROS) and the accumulation of mitochondrial precursor proteins in the cytosol. Detection of these signaling molecules involves the oxidation of cysteine residues on the cytosolic co-chaperone DNAJA1, which in turn activates the transcription factor HSF1 to initiate the UPRmt. This work uncovered a novel role for DNAJA1 as a cytosolic surveillance molecule in UPRmt signaling. Reymond’s lab will continue to focus on exploring non-classical roles of chaperones beyond their traditional function in protein folding, specifically in mediating cell signaling and responding to changes in the cellular environment, including redox shifts. Ultimately, his lab aims to explore the relevance of these non-classical chaperone roles in both physiological and disease contexts, including aging.

 

Exciting update! The early bird registration and abstract submission deadlines for poster presentations at SFRR-I have been extended!

The early bird registration deadline for the 22nd SFRR-I Biennial Meeting hosted by the Society for Free Radical Research - Europe “The New Era of Redox Biology: from Basic Biochemistry to Redox Omics” to be held in Galway, Ireland, June 03 - 06, 2025 has been extended!

The early bird registration deadline is now 3rd April 2025.

The deadline for abstract submission for a poster presentation, has also been extended to 3rd April 2025.

For more details about the conference and the details of the program, including the symposia and keynote lectures, please visit the conference website: https://www.sfrrgalway2025.com/ 

 

Summary of March’s webinar:

On March’s webinar we learnt about “Redox, exercise and nutrition” with three wonderful talks by Stephen Bailey, Edziu Franczak and Lewan Parker. If you didn’t have a chance to follow the webinar, here’s a summary for you. Remember that you can also watch the recordings of the webinars through the SFRR-E intranet.

 

Influence of dietary nitrate supplementation on skeletal muscle redox processes, physiological responses and exercise performance

Stephen Bailey, PhD
Loughborough University, UK

Nitrate power: Fueling muscle performance. In this webinar, Dr. Stephen Bailey explored how dietary nitrate supplementation influences skeletal muscle redox status, physiological responses, and exercise performance. Dr. Bailey’s research demonstrates that nitrate supplementation can reduce the oxygen cost of exercise, improve endurance, and enhance muscle contractility, particularly in conditions where oxygen availability is limited. Additionally, he showed how nitrate affects oxidative stress and redox signaling in skeletal muscle, which plays a crucial role in muscle adaptation and fatigue resistance. By optimizing NO bioavailability, dietary nitrate has the potential to boost athletic performance and improve muscle function under conditions of intense exercise. Dr. Bailey’s work provides valuable insights into how nutrition-based strategies can support metabolic and cardiovascular health, making nitrate supplementation a promising tool for improving exercise capacity and overall well-being.

 

 

Mitochondrial quality control: Another reason why women are superior

Edziu Franczak, PhD candidate
University of Kansas Medical Center, Kansas, USA

Uncovering women superiority. Edziu's presentation explored how mitochondrial quality control may contribute to women’s innate protection against metabolic dysfunction-associated steatotic liver disease (MASLD). Particularly, his talk emphasized how estrogen influences mitochondrial function in the liver, particularly in response to exercise and dietary metabolic stressors such as high-fat, high-sucrose diets. Edziu’s work suggests that estrogen-related signaling enhances mitochondrial respiratory capacity and promotes more effective quality control mechanisms, which could explain why females tend to have a lower risk of MASLD compared to males. By studying rodent models, he provided evidence that estrogen supports liver health and further investigated whether these protective mechanisms could inform new treatment strategies for MASLD. Importantly, his findings highlight the importance of sex differences and divergence in aerobic capacity in metabolic disease research and suggest that targeting mitochondrial function may be a promising therapeutic avenue.

 

 

The effect of exercise and nutrient ingestion on biomarkers of redox homeostasis

Lewan Parker, PhD
Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Australia

Redox interindividual variability. Dr. Parker's talk focused on how exercise and nutrient ingestion affect redox homeostasis, specifically biomarkers related to oxidative stress and antioxidant defenses. In his recent work, Dr. Parker examined the individualized responses to exercise and high-glucose ingestion, and mainly how these factors influence oxidative balance in healthy individuals. His research proposes a significant degree of variability between individuals in response to exercise and nutritional interventions, highlighting the role of interindividual differences in redox homeostasis and adaptations. Notably, Dr. Parker’s research proposes that this variability is crucial for developing personalized exercise and nutrition approaches in managing chronic diseases such as type 2 diabetes and cardiovascular diseases. 

More information about the ECR Subcommittee can be found on the SFRR-E website (ECR Committee), while regular updates can be found on Twitter (@SFRR_Europe), Instagram (@sfrr_ecr) and LinkedIn (SFRR-E). For any question or suggestion you might have, you can contact us via email: This email address is being protected from spambots. You need JavaScript enabled to view it..

Hope to see you online for our next Webinar Series appointment,

The ECR subcommittee

 

Upcoming events:

UK Redox Network Meeting

• 28 April 2025
• Location: ICR Administrative Building, 123 Old Brompton Road (SW7 3RP), Chelsea, London
• Organisers: Joerg Mansfeld, Olena Rudyk & Giovanni Mann
• Speakers include: James Nathan, Elizabeth Veal, Paraskevi Kritsiligkou, Joseph Burgoyne
• Register here: https://forms.office.com/e/8Zt9Kq2dag 
• DEADLINE ABSTRACT SUBMISSION for oral and poster presentations: 31st MARCH 2025!

 

22nd SFRRI Biennial Meeting

• The New Era of Redox Biology: from Basic Biochemistry to Redox Omics
• 3 - 6 June 2025
• Location: Galway, Ireland
• Deadlines: Early Bird Registration and abstract submission for poster presentation: 4 April 2025
• Further information: https://www.sfrrgalway2025.com 
• Don’t miss out on the fascinating satellite symposia!

 

FASEB Science Research Conference. Ferroptosis, Oxidative Stress, and Lipid Metabolism

• 27 - 31 July 2025
• Location: Scottsdale, Arizona
• Deadlines:
  • Abstract Submission: 1 June 2025
  • Early Registration: 15 June 2025
  • Housing: 13 July 2025
• Further information: https://events.faseb.org/event/11797f9e-df16-42b9-9c47-f1e06713c4fb/summary  

 

EMBO Workshop: Thiol based redox switches: From chemistry to physiology and pathology

• 13 - 18 September 2025
• Location: Sant Feliu de Guixols, Spain
• Abstract Submission Deadline: 18 May 2025
• https://meetings.embo.org/event/25-thiol-switches 

 

Interesting Redox Papers:

Marker, T., Steimbach, R.R., Perez-Borrajero, C. et al. Site-specific activation of the proton pump inhibitor rabeprazole by tetrathiolate zinc centres. Nat Chem (2025). https://doi.org/10.1038/s41557-025-01745-8 

Miró-Vinyals, C., Emmert, S., Grammbitter, G., et al. Characterization of the glutathione redox state in the Golgi apparatus. Redox Biol (2025). https://doi.org/10.1016/j.redox.2025.103560 

Zuhra, K., Petrosino, M., Janickova, L. et al. Regulation of mammalian cellular metabolism by endogenous cyanide production. Nat Metab (2025). https://doi.org/10.1038/s42255-025-01225-w 

Steglich, M., Larrieux, N., Zeida, A., et al. Human glutathione transferases catalyze the reaction between glutathione and nitrooleic acid. J Biol Chem (2025). https://doi.org/10.1016/j.jbc.2025.108362 

Borbényi-Galambos, K., Erdélyi, K., Ditrói, T., et al. Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma. Cell Metab (2025). https://doi.org/10.1016/j.cmet.2025.01.021 

Noce, B., Marchese, S., Massari, M., et al. Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor. J Med Chem (2025). https://doi.org/10.1021/acs.jmedchem.4c02644 

 

Insightful Redox Reviews:

Lancaster, G.L. & Murphy, A.J. Do physiological changes in fatty acid composition alter cellular ferroptosis susceptibility and influence cell function? J Lipid Red (2025). https://doi.org/10.1016/j.jlr.2025.100765 

Grimmett, Z.W., Schindler, J.C. & Stamler, J.S. Gases define redox signalling: NO, H2S, O2 … and cyanide. Nat Metab (2025). https://doi.org/10.1038/s42255-025-01229-6 

Park, W.Y., Montufar, C. & Zaganjor, E. Mitochondrial substrate oxidation regulates distinct cell differentiation outcomes. Trends Cell Biol (2025). https://doi.org/10.1016/j.tcb.2025.02.004 

Hartsema, E.A., Hemmling, H. & Hawkins, C.L. Comparative reactivity of hypohalous acids with proteins: Chemistry, biological effects and consequences. Adv Redox Res (2025). https://doi.org/10.1016/j.arres.2025.100119 

 

Latest Redox Preprints:

Zeisel, L., Dessen-Weissenhorn, L., Scholzen, K.C., et al. Bicyclic selenenyl sulfides tune stepwise rates of thiol/selenol addition, resolution, and cyclisation, to reveal cellular constraints for bioreductive probes targeting mammalian thioredoxin reductase. ChemRxiv (2025). https://doi.org/10.26434/chemrxiv-2025-6vbn2 

Zimmermann, J., Lang, L., Malo Pueyo, J., et al. Heterooligomerization drives structural plasticity of eukaryotic peroxiredoxins. BioRxiv (2025). https://doi.org/10.1101/2025.03.03.641172 

Button, E.L., Lewis, J.B., Dwyer, E., et al. The 1-Cys peroxiredoxin, PRDX-6, suppresses a pro-survival response, including the Flavin monoxygenase, FMO-2, that protects against fungal and bacterial infection. BioRxiv (2025). https://doi.org/10.1101/2025.03.06.640586 

 

Call for papers:

Journal: Redox Biochemistry and Chemistry

• Special Issue: Spatial analysis and new methods of identifying and quantifying intracellular oxidants
• Submission deadline: 31 August 2025
• More information: https://www.sciencedirect.com/special-issue/320420/spatial-analysis-and-new-methods-of-identifying-and-quantifying-intracellular-oxidants 

 

Redox Job Opportunities:

Remember that if there’s an open position in your lab for early career researchers and you would like to advertise it in our newsletter, just write us an email (This email address is being protected from spambots. You need JavaScript enabled to view it.) containing the following information:

• Kind of position: (PhD student, Postdoc, etc)
• Research topic
• Institute/University
• Deadline
• Contact information
• Further information about the position (if any)

Dear colleagues, 

We are celebrating our birthday! It’s already been 3 years since the formation of the ECR subcommittee! We are very happy to reflect on what we have achieved so far for early career researchers, and we thank you all for the support that you have shown to us along the way. For more years to come!

In today's newsletter, we will do a sum-up of how much the ECR subcommittee has grown its first three years. We will also announce the upcoming March’s webinar discussing redox, exercise and nutrition and share with you a summary of February’s webinar. At the end of the newsletter, as always, you can also find a collection of upcoming events with important deadlines, some suggestions of interesting redox reads recently published, open call for papers and job opportunities for young redox researchers.

Three years of the ECR subcommittee: what we have achieved so far!

It seems like yesterday when this exciting journey of creating an ECR subcommittee composed by early career researchers and for early career researchers began. And look at us now! It’s been three years of intense work, networking and learning. This is what we have achieved so far:

• Webinar series: On the 7^th February 2022, we launched our webinar series “Emerging leaders in redox biology”. So far we’ve organised 19 webinars on a wide variety of topics: from NADPH oxidases to persulfides, from aging to exercise, from peer review to mental health. We are delighted to see the great reception these webinars have had, and we are already working in the next edition!
  
  
• Social media: We have created accounts on different platforms. Many of you follow us on our fun and creative Instagram account (https://www.instagram.com/sfrr_ecr/), so far we have 1026 followers! Some of you are more into the professional-oriented LinkedIn where we already have 378 followers (https://www.linkedin.com/company/sfrr-e-ecr/)! Or maybe you prefer our X account that counts 946 followers. However we are transitioning to Bluesky, so please follow us there (https://bsky.app/profile/sfrre-ecr.bsky.social)!
  
  
• SFRR-E meetings: Starting in Ghent 2022, we have had the opportunity to organise some activities at the annual SFRR-Europe conferences. Thanks to your participation and interest in these events, we’ve been gradually increasing the number of activities that we plan. Last year in Istanbul we organised a successful ECR networking event, a meet the professor session, two sunrise seminars and the first ECR symposium with only young speakers! We will soon announce what we have planned for Galway conference, but you can check the schedule for some hints https://www.sfrrgalway2025.com/ 
  
  
• Mentoring program: In 2023 we created a mentoring program in which we paired young scientists with senior scientists to get career and professional advice. We have run this program now for two cohorts and organised the first mentoring lunch at Istanbul’s conference last year. We are over the moon with your positive experiences, knowing that it is helping you grow makes all the efforts worth it! We are happy to announce that the program will run for a third year, stay tuned!
  
  
• Editorial mentoring program: We created a new editorial mentoring program in which selected young scientists are paired with an editor of the best redox journals for a year to learn how editorial work functions. The program is now running and the first cohort is getting hands-on experience.

The ECR subcommittee works very hard to deliver all these. We are very pleased that our efforts are so well appreciated and we are very thankful for all the feedback and the support you have given us. Recently FEBS asked us to write a piece about our work highlighting our achievements. You can see it here: https://network.febs.org/posts/what-is-the-ecr-subcommittee-of-the-sfrr-europe-up-to-the-new-kid-on-the-block 

 

Next Webinar series “Emerging leaders in redox biology”

The next webinar of the year will take place on March 4th, 2025, at 15:00 CET, focusing on the hot topic “H₂S redox signaling” with featured speakers Stephen Bailey, Edziu Franczak and Lewan Parker. 

Influence of dietary nitrate supplementation on skeletal muscle redox processes, physiological responses and exercise performance

Stephen Bailey, PhD

Loughborough University, UK

Stephen’s research focuses on exercise and nutritional interventions to improve nitric oxide production, cardiovascular health, oxidative metabolism and exercise performance.  Stephen has published over 150 research outputs on these topics.  He is a Fellow of the European College of Sport Science, a member of The Physiological Society, and he serves on the editorial board of two international journals and as a judge for the European Specialists Sports Nutrition Awards.

 

Mitochondrial quality control: Another reason why women are superior

Edziu Franczak, PhD candidate

University of Kansas Medical Center, Kansas, USA

Edziu is a PhD student in Dr. John Thyfault's lab at the University of Kansas Medical Center. His research focuses on understanding the mechanisms that regulate the pathogenesis and treatment of metabolic dysfunction-associated steatotic liver disease (MASLD) in the context of exercise and dietary metabolic stressors. Specifically, his research aims to understand how estrogen-mediated signaling modulates hepatic mitochondrial respiratory capacity and quality control mechanisms that may foster innate protection against MASLD in female rodent models. 

 

The effect of exercise and nutrient ingestion on biomarkers of redox homeostasis

Lewan Parker, PhD

Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Australia

Dr Parker is a joint NHMRC & Heart Foundation Early Career Fellow and leader of the Redox Regulation of Health and Disease research group at Deakin’s Institute for Physical Activity and Nutrition (IPAN). Dr Parker's internationally recognised research program explores how physical activity, redox biology, bone metabolism, and vascular health, regulate glycaemic control, exercise capacity, and cardiometabolic health and disease. Through the identification of novel mechanisms, his research continues to explore new ways to harness exercise and nutrition for the prevention, management, and treatment of chronic diseases such as type 2 diabetes and cardiovascular disease.

Summary of February’s webinar:

On February's webinar we learnt about “H₂S redox signaling” with two inspiring talks by Denisse Scufi and Jan Miljkovic. If you didn’t have a chance to follow the webinar, here’s a summary for you. Remember that you can also watch the recordings of the webinars through the SFRR-E intranet. 

Hydrogen sulfide role in stomatal immunity

Denisse Scufi, PhD

Signaling Mechanisms in Plants Lab, IIB-CONICET-UNMdP, Mar Del Plata, Argentina

Shut the Pore! - Stomata are natural pores on the leaf surface that help plants exchange gases with the environment. Stomata also function as entry points for pathogens. Plants can regulate stomata closure by different molecular mechanisms, including phytohormones, hydrogen sulfide (H₂S), or the recognition of peptide effectors from the pathogen, among others. In this webinar, Dr. Denise Scuffi shared their latest work characterising the role of H₂S in the pathogen-induced stomata closure. This was evaluated using a mutant line in cytosolic L-CYSTEINE DESULFHIDRASE 1 (DES1), the main source of cytosolic H₂S in plants. They proved that stomata closure in des1 plants does not happen after exposition to either the pathogen or the effector. A response that can be reversed in des1 plants is treating these mutants with an H₂S donor. Moreover, they further conclude that the role of H2S in regulating stomata closure is also linked with the control of hydrogen peroxide (H₂O₂) and intracellular calcium homeostasis. We invite everyone to check Dr. Scuffi’s research in their latest preprint (https://doi.org/10.1101/2025.02.14.638267).

 

Mitochondria-Targeted Protection Against Cardiac Ischemia-Reperfusion via Rapid Persulfide and H2S Release

Jan Miljkovic, PhD

MRC Mitochondrial Biology Unit, University of Cambridge, UK

Hydrogen Sulfide to the Heart- In this webinar, Dr. Jan Miljkovic presented his work on creating, designing, and applying sulfur-containing molecules to treat the damage produced by cardiac ischemia reperfusion (IRI). These molecules act as hydrogen sulfide (H₂S) donors, which has been demonstrated to be beneficial for cardiac pathologies. The multiple roles of H₂S include scavenging ROS/RNS, binding to the metal centres of proteins, and promoting a post-translational modification called S-sulfhydration. In their novel approach, Dr. Miljkovic showed how a targeted delivery of H₂S from mitochondria, using targeted compounds that serve as H₂S donors, could represent a therapeutic opportunity to alleviate IRI. Among these compounds, using MitoPerSulf before IRI showed a significant cardioprotective effect in a mouse model, limiting the IRI-associated damage. These results show MitoPerSulf as a cardioprotective strategy with great potential against the damaging effects of IRI when applied in a precise time window before the tissues become ischemic. For more details, please check Dr. Miljkovic’s work published in Redox Biology (https://doi.org/10.1016/j.redox.2022.102429).

 

More information about the ECR Subcommittee can be found on the SFRR-E website (ECR Committee), while regular updates can be found on Twitter (@SFRR_Europe), Instagram (@sfrr_ecr) and LinkedIn (SFRR-E). For any question or suggestion you might have, you can contact us via email: This email address is being protected from spambots. You need JavaScript enabled to view it..

Hope to see you online for our next Webinar Series appointment,

The ECR subcommittee

 

Upcoming events:

UK Redox Network Meeting

• 28 April 2025
• Location: London, UK

 

22nd SFRRI Biennial Meeting

• The New Era of Redox Biology: from Basic Biochemistry to Redox Omics
• 3 - 6 June 2025
• Location: Galway, Ireland
• Deadlines:
  • Travel Grant Applications: 10 January 2025
  • Abstract Submission: 10 February 2025
  • Early Bird Registration: 31 March 2025
• Further information: https://www.sfrrgalway2025.com

 

 FASEB Science Research Conference. Ferroptosis, Oxidative Stress, and Lipid Metabolism

• 27 - 31 July 2025
• Location: Scottsdale, Arizona
• Deadlines:
  • Abstract Submission: 1 June 2025
  • Early Registration: 15 June 2025
  • Housing: 13 July 2025
• Further information: https://events.faseb.org/event/11797f9e-df16-42b9-9c47-f1e06713c4fb/summary

 

EMBO Workshop: Thiol based redox switches: From chemistry to physiology and pathology

• 13 - 18 September 2025
• Location: Sant Feliu de Guixols, Spain
• Abstract Submission Deadline: 18 May 2025
• https://meetings.embo.org/event/25-thiol-switches

 

Interesting Redox Papers:

Cobley, J.N., Chatzinikolaou, P.N. & Schmidt, C.A. The nonlinear cysteine redox dynamics in the i-space: A proteoform-centric theory of redox regulation. Redox Biol (2025). https://doi.org/10.1016/j.redox.2025.103523

Zhang, Q., Liu, X. & Wei, Q. Apoptotic breast cancer cells after chemotherapy induce pro-tumour extracellular vesicles via LAP-competent macrophages. Redox Biol (2025). https://doi.org/10.1016/j.redox.2024.103485

Cendali, F.I., Lisk, C., Dzieciatkowska, M., et al. Increased exercise tolerance in humanized G6PD-deficient mice. Blood Adv (2025). https://doi.org/10.1182/bloodadvances.2024013968

Smiriglia, A., Lorito, N., Bacci, M., et al. Estrogen-dependent activation of TRX2 reverses oxidative stress and metabolic dysfunction associated with steatotic disease. Cell Death Dis (2025). https://doi.org/10.1038/s41419-025-07331-7

Li, H., Furusawa, T., Cavero, R., et al. Metabolic dependency mapping identifies Peroxiredoxin 1 as a driver of resistance to ATM inhibition. Redox Biol (2025). https://doi.org/10.1016/j.redox.2025.103503

Valeros, J., Jerome, M., Tseyang, T., et al. Rhodoquinone carries electrons in the mammalian electron transport chain. Cell (2025). https://doi.org/10.1016/j.cell.2024.12.007

Torres-López, M., Spiller, P.F., Gao, L., et al.. Acute oxygen sensing by arterial chemoreceptors with a mutant mitochondrial complex I ND6 subunit lacking reverse electron transport. FEBS Lett (2025). https://doi.org/10.1002/1873-3468.70017

Morton, K.S., George, A.J. & Meyer, J.N. Complex I superoxide anion production is necessary and sufficient for complex I inhibitor-induced dopaminergic neurodegeneration in Caenorhabditis elegans. Redox Biol (2025). https://doi.org/10.1016/j.redox.2025.103538

Petrovic, D., Slade, L., Paikopoulos, Y., et al. Ergothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation. Cell Metab (2025). https://doi.org/10.1016/j.cmet.2024.12.008

 

Insightful Redox Reviews:

Liu, P., Liu, Z.Y., Mao, S., et al. Targeted mitochondrial function for cardiac fibrosis: An epigenetic perspective. Free Radic Biol Med (2025). https://doi.org/10.1016/j.freeradbiomed.2025.01.001

Chrzan, N. & Hartman, M.L. Copper in melanoma: At the crossroad of protumorigenic and anticancer roles. Redox Biol (2025). https://doi.org/10.1016/j.redox.2025.103552

Guo, Q., Tang, Y., Wang, S & Xia, X. Applications and enhancement strategies of ROS-based non-invasive therapies in cancer treatment. Redox Biol (2025). https://doi.org/10.1016/j.redox.2025.103515

Fuentes-Lemus, E., Usgame, K., Fierro, A. & López-Alarcón, C. Enzymes of glycolysis and the pentose phosphate pathway as targets of oxidants: Role of redox reactions on the carbohydrate catabolism. Redox Biochem Chem (2025). https://doi.org/10.1016/j.rbc.2025.100049 

 

Lastest Redox Preprints:

Lang, L., Leiskau, L., Thullen, L. & Deponte, M. H2S is a potential universal reducing agent for Prx6-type peroxiredoxins. BioRxiv (2025). https://doi.org/10.1101/2025.02.13.638076

Wyckelsma, V.L., Murgia, M., Kamandulis, S., et al. Antioxidant supplementation blunts the proteome response to three weeks of sprint interval training preferentially in human type 2 muscle fibres. BioRxiv (2025). https://doi.org/10.1101/2025.01.27.634979

 

Call for papers:

• Journal: Free Radical Biology and Medicine
• Special Issue: Redox medicine: Translation of Basic science to the Clinic
• Submission deadline: 1 March 2025
• More information: https://www.sciencedirect.com/special-issue/314690/redox-medicine-translation-of-basic-science-to-the-clinic

   

Redox Job Opportunities:

Remember that if there’s an open position in your lab for early career researchers and you would like to advertise it in our newsletter, just write us an email (This email address is being protected from spambots. You need JavaScript enabled to view it.) containing the following information:

• Kind of position: (PhD student, Postdoc, etc)
• Research topic
• Institute/University
• Deadline
• Contact information
• Further information about the position (if any)